FOR MOST PATIENTS, DRY EYE SYMPTOMS HAVE ANEPISODIC IMPACT
FLARES: THE SPEED BUMPS OF DRY EYE
Most patients with Dry Eye suffer from short-term, episodic exacerbations—Dry Eye Flares.1-3
Many patients don’t suffer from continuous symptoms.3
DRY EYE: An Inflammatory Disease That May Impact Quality Of Life
Inflammation is a KEY DRIVER OF THE PATHOGENESIS AND SYMPTOMATOLOGY of Dry Eye4,5
The symptoms of Dry Eye, such as
ocular discomfort, grittiness, itchiness, stinging, tired eyes, and blurred vision, can have a substantial impact on quality of life (QOL)6
- PATIENTS WITH DRY EYE WERE APPROXIMATELY3X MORE LIKELYto have problems with reading, engaging in professional work, using a computer, watching television, or driving7
- OCULAR SURFACE DAMAGE CANCOMPROMISE THE RESULTSof corneal, cataract, and refractive surgery6
The symptoms of Dry Eye often manifest as short-term, episodic exacerbations—Dry Eye Flares1-3
WHAT ARE DRY EYE FLARES?
EPISODIC FLARE Is a Common Feature of Chronic Inflammatory Diseases such as Dry Eye
Many chronic diseases have episodic exacerbations of signs and symptoms versus consistent, continuous disease. These episodic exacerbations are often called ‘flares.‘8
These diseases include:
DRY EYE HAS A SIMILAR PATTERN.9
Dry Eye Flares are rapid-onset, inflammation-driven responses to a variety of triggers, which may not be adequately managed with a patient’s ongoing maintenance therapy, such as artificial tears and daily, chronic Rx therapies5,10-12


Triggers may include seasonal allergies, A/C use, digital screen time, air travel, contact lens wear, medications, and cataract and refractive surgery6,13,14
In recent, major surveys, MOST PATIENTS WITH DRY EYE REPORTED SUFFERING DRY EYE FLARES1-3*Yet Many Do Not Tell Their Eye Care Professionals (ECPs)
-
~80%
OF PATIENTS WITH DRY EYE
SUFFER FLARES1-3
-
45%
OF PATIENTS WITH DRY EYE REPORT HAVING
PRIMARILY FLARES
INSTEAD OF CONTINUOUS SYMPTOMS3
Yet ECPs say thatONLY
~40%
OF THEIR PATIENTS SUFFER FROM DRY EYE FLARES15†
Have your patients discussed their Dry Eye Flares with you?
UNCOVERING DRY EYE FLARES
Questions you can ask to learn if your patients are experiencing Dry Eye Flares:
- Are there times (episodes) when your Dry Eye symptoms become more severe and your eyes feel worse than they typically feel?
- Do you have these episodes even when you take artificial tears or Rx therapy?
If your patients answer 'Yes,' they could be experiencing Dry Eye Flares.
*Data based on:
- Study of Dry Eye Sufferers conducted by Multi-sponsor Surveys, Inc; trended series; 2018 study, 15th in series (N=751)2; 2020 study, 16th in series (N=774)3
- 2018 Lieberman Dry Eye Patient Survey (N=297)1,2
†Based on 2020 Reason Research, LLC ECP survey (N=101 ophthalmologists and N=100 optometrists).15
UNMET NEEDS EXIST IN THE TREATMENT OF DRY EYE FLARES
Artificial tears do not address underlying inflammation and provide only symptomatic, transient relief16

In a Recent Survey,
~80%
OF PATIENTS USING ARTIFICIAL TEARS AND/OR OTHER CURRENTLY AVAILABLE DRY EYE PRODUCTS REPORTED THAT THEY STILL SUFFER FLARES15*
- Dry Eye can have a substantial impact on patients’ quality of life6
-
Many patients with Dry Eye suffer primarily Dry Eye Flares, instead of continuous symptoms3
- Your patients may be suffering from Dry Eye Flares, but not discussing them with you1-3
Ask your patients
about their experience with Dry Eye Flares
KALA IS COMMITTED to ongoing research in the TREATMENT OF DRY EYE
*Data based on the 2018 Lieberman Dry Eye Patient Survey (N=297).